Mitochondrial ageing in rat brain areas and human fibroblasts

(2010). 9-Methyl-beta-carboline has restorative effects in an animal model of Parkinson's disease. (2009) From protons to OXPHOS supercomplexes and Alzheimer's disease: structure-dynamics-function relationships of energy-transducing membranes. (2009). Reactive oxygen species are involved in senescence of human cells independently from irradiation exposure. GSI Sci. (2009). Oxidative stress and telomere shortening in normal human fibroblasts after irradiation with X-rays. effect of X-ray irradiation on the native mitochondrial proteome, ROS generation and physiology in senescent human fibroblasts. (2011). Alterations in the mitochondrial proteome of three different human cell lines after X-ray and heavy ion irradiation. Title: Age-dependent changes in mitochondrial protein profile of rat brain Title: Changes in ROS and mitochondrial proteome during senescence of irradiated human cell lines Guest lecture at the Title: Mitochondrial proteome profiling using 2D blue-native/SDS-PAGE Title: Age-dependent alterations in the supramolecular architecture of the oxidative phosphorylation complexes in rat cortex 3rd Symposium on the Role of Mitochondria in Conserved Mechanisms of Ageing Title: Age-dependent changes in mitochondrial protein profile and OXPHOS superstructures in rat brain 17. Title: Comparative studies on age-dependent alterations in the mitochondrial proteome of different brain regions Title: Supramolecular organisation of OxPhos complexes changes during ageing in various regions to a different extent Title: Effect of radiation on the mitochondrial proteome of human cell cultures Title: The supramolecular organisation of OXPHOS complexes in different rat brain regions changes during ageing Title: Age-dependent alterations in the supramolecular organisation of OXPHOS complexes in different brain regions Title: Age-dependent alterations in the supramolecular architecture of the oxidative phosphorylation complexes in rat cortex MiMage/LINK-AGE Joint Summer School " Models and Methods in Ageing Research " , Les Diablerets (2007), Switzerland – Poster Awards Title: Age-dependent alterations in the supramolecular architecture of the oxidative phosphorylation complexes in rat cortex 3rd Symposium on the Role of Mitochondria in Conserved Mechanisms of Ageing Title: Age-dependent changes in mitochondrial protein profile and OXPHOS superstructures in rat brain X XI ACKNOWLEDGEMENT OF SCIENTIFIC COLLABORATIONS I am grateful to the team of the Biophysik group at the " Gesellschaft für Schwerionenforschung " (GSI, Darmstadt, Germany) for their help during my experiments in providing me all facilities for cell culture and irradiation. In particular, I would like to express my graduate to: Prof. Dr. Marco Durante (head of the department) for giving me the opportunity to work in his group at GSI and for all discussions about my thesis; Dr. Claudia Fournier, helping me in planning …